Mazinger Otome depicts the mechas of the Mazinger franchise and Steel Jeeg series as androids where they fit into regular life. It follows the android girls that make up the cast as they deal with life in high school and from the school delinquents the Mechanical Beast Army. The main protagonist is Seto Magami, an android based on the Mazinger Z who is treated as the granddaughter of Juzo Magami. Later with the introduction of the New Mazinger Army, there are heated arguments and fights between them and the originals.

Mazinger Otome depicts the mechas of the Mazinger franchise and Steel Jeeg series as androids where they fit into regular life. It follows the android girls that make up the cast as they deal with life in high school and from the school delinquents the Mechanical Beast Army. The main protagonist is Seto Magami, an android based on the Mazinger Z who is treated as the granddaughter of Juzo Magami. Later with the introduction of the New Mazinger Army, there are heated arguments and fights between them and the originals.