Returning after his mother's murder to the semi-fictional city of Los Santos (based on Los Angeles), Carl Johnson, a former gang banger, must take back the streets for his family and friends by gaining respect and once again gaining control over the streets. However, a story filled with crime, lies and corruption will lead him to trudge the entire state of San Andreas (based on California and Nevada) to rebuild his life.

Returning after his mother's murder to the semi-fictional city of Los Santos (based on Los Angeles), Carl Johnson, a former gang banger, must take back the streets for his family and friends by gaining respect and once again gaining control over the streets. However, a story filled with crime, lies and corruption will lead him to trudge the entire state of San Andreas (based on California and Nevada) to rebuild his life.